As compared to other tools, Cyberduck has optimized options for organizing and bookmarking, like Spotlight Importer, history, etc.
There is also support for using Google Cloud Storage and Rackspace Cloud Files, making it easy for you to deal with your sites. It provides support for FTP, SFTP, OpenStack Swift, WebDAV, and Amazon S3. If you do care about the looks of the best FTP clients you use, you would be interested in using Cyberduck. Cyberduck is yet another open-source FTP Client that provides support for Windows and Mac OS X.
